Visual Communication of Neurovascular Development

Contributors: Lydia Gregg MA, CMI, FAMI, Jeff S. Mumm PhD, Gerard A. Lutty PhD, David T. White PhD, Gary Lees MA, CMI, FAMI, Philippe Gailloud MD
Embryo

The embryological development of vertebrate neurovasculature is a visually stunning cascade of events, and represents an area of interest for clinical and basic science disciplines such as vascular neurosurgery, interventional neuroradiology, developmental biology, and neuroscience. This work represents an ongoing project, funded in part by the Johns Hopkins Catalyst Award program, to create visualizations that teach neurovascular development while continuing a history of developmental biology visualization by medical illustrators at Johns Hopkins University School of Medicine.

Zebrafish Optic and Ocular branches

Similar to humans, the developing zebrafish eye is supplied by the intraocular hyaloid vasculature, the superficial ciliary vasculature, and the morphologically distinct choroidal vasculature. Here we provide a summary of the development of these vessels based on an observational study in collaboration with the Mumm Lab in the Johns Hopkins Department of Ophthalmology.

Human Ophthalmic and Ocular branches

The human ophthalmic artery and the embryonic pathways leading to aberrant ophthalmic artery anatomy have been areas of interest in the clinical literature since the publication of Dorcas Padget’s research on neurovascular development. Understanding of anomalous ophthalmic arteries and anastomotic branches is essential in preventing iatrogenic damage during surgical and endovascular procedures.

Historic Medical Illustrators in Embryology